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Understanding Peyronie’s Disease


How MSTR® Offers a New Approach

Peyronie’s disease (PD) is a fibrotic condition of the penis that affects men’s physical, sexual, and emotional well-being. Despite its prevalence, it remains little discussed - especially compared to the attention given to scarring conditions in women such as cesarean or hysterectomy scars.

 

Over the years of recorded clinical success using MSTR® for PD, we believe we are in a position to confidently assert that PD can be, at least in some cases, help men who are affected with PD.

For educational purposes.

What is Peyronie's Disease?

1

Peyronie’s disease is a condition in which scar tissue (plaque) forms within the tunica albuginea — the dense fibrous sheath that surrounds the erectile chambers of the penis. Unlike arterial plaque seen in heart disease, PD plaques are scar tissue that can cause:

  • Curvature or bending of the penis

  • Shortening or narrowing of the shaft

  • Painful erections

  • Difficulty with intercourse
     

The scar tissue is a result of abnormal wound healing following repetitive micro-trauma to the tunica during erections or sexual activity. Not every man who experiences penile strain will develop PD — but in those who do, the body’s repair mechanisms lay down excessive collagen, leading to fibrotic plaque formation.

How Common Is Peyronie’s Disease?

2

PD is more common than many people realize, and prevalence increases with age. Estimates vary depending on how data are collected, but reliable studies suggest:
 

  • United States: Up to 10–13% of adult men report symptoms consistent with PD when including undiagnosed cases, with lower percentages when only diagnosed cases are counted.

  • United Kingdom: Estimated at around 3–10% of men, with higher prevalence in middle-aged and older men.

  • Germany: A population survey reported PD in approximately 3.2% of men aged 30–80, increasing with age.

  • Australia: While large population studies are limited, clinical estimates suggest up to ~9% of men may show signs of PD or related symptoms.
     

These statistics reflect that PD is not rare, and because many men don’t seek help due to embarrassment or lack of awareness, the true prevalence may be higher.

How Peyronie’s Disease Affects Men

3

Physical Impact

  • Penile curvature & deformity: Can make intercourse difficult or impossible

  • Pain during erection: Especially in early stages

  • Erectile dysfunction: Often co-occurs, complicating sexual health

Emotional & Psychological Impact

Living with PD can take a real psychological toll:

  • Reduced self-confidence

  • Anxiety or avoidance of intimacy

  • Depression or emotional distress

  • Strained relationships
     

Because it’s a private and sensitive condition, many men cope silently, delaying or avoiding treatment.

Causes of Peyronie’s Disease 

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Causation

Peyronie’s Disease is an acquired fibrotic condition affecting the tunica albuginea of the penis.

Core Mechanism

  • Micro trauma to the erect penis

  • Repetitive mechanical stress

  • Incomplete tissue healing

  • Aberrant collagen deposition

  • Plaque formation within the tunica albuginea

  • Loss of elasticity in the affected region

Risk Factors

  • Age (most common 40–70)

  • Diabetes

  • Smoking

  • Hypertension

  • Dupuytren’s contracture

  • Connective tissue disorders

  • Penile trauma (recognized or unrecognized)

  • Pelvic surgery history

Phases of Peyronie’s Disease 

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Acute (inflammatory phase)

Duration: approximately 6-18 months - commonly 9-12 months
 

What happens during this phase?

  • Penile pain (especially during erection)

  • Progressive or changing curvature

  • Palpable plaque developing

  • Possible indentation or narrowing

  • Emotional distress often highest during this period

This phase reflects:

  • Active inflammation

  • Ongoing collagen deposition

  • Tissue remodelling that is not yet stable

Chronic Phase (Stable Phase)

Typical onset begins once curvature has been stable for at least 3–6 months Usually around 12–18 months from symptom onset

 

What happens during this phase?

  • Little or no pain

  • Curvature stabilises

  • Plaque becomes more fibrotic and consolidated

  • Erectile dysfunction may persist (if present)

In this stage:

  • Active inflammation has largely resolved

  • Structural changes are considered stable

  • Spontaneous improvement is less common

Case study

Published with client consent for medical-educational purposes. Images are anonymised and used in accordance with privacy regulations.

Peyronies_disease.jpg

Presentation:

  • Healthy sexually active Male 65yo

  • Painful penis during erection and sexual intercourse.

  • Curve in penis when erect.

  • No prior injury or event noted by the patient.

History:

  • Patient started to notice some minor contracture in the dorsal aspect of his penis during erection about 12mths ago. Initially no pain, as time advanced he noticed more obvious contraction.

  • About 6 months ago he started experiencing significant pain during sexual intercourse and that his penis shaft was curving upwards and back towards his body when erect. During erection the pain was on the lower aspect of the shaft.

  • The pain increased to the stage that he was unable to have sexual intercourse. He noticed that his penis was significantly curved back towards his body when erect and the pain was on the lower aspect of the shaft when engorged.

  • Pt was referred to a urologist 4mths ago, he was Dx with Peyronie’s, unfortunately no scan available.

  • Diagnosed with 2 points of fibrous tissue on the distal aspect of the shaft, one low about ½ cm from the dorsal aspect of the Root and the second about 1/2cm from the dorsal aspect of the Glans.

  • He was told that there is no medical treatment availble for this condition other than surgery – which is always a last resort.

  • Patient was referred to a urology clinic where ‘Alternative treatment’ was advised using a device that literally stretched the scar tissue to force release.

Treatment regime – 5 minute application twice daily (morning and evening) for 1 week then review.

Patient followed the agreed treatment regime for 2 weeks.

  • Day 3 – Patient noticed a slight release of the lower fibrous tissue.

  • Day 5 – Patient noted that whilst erect his Glan appeared to be further from his body and lower.

  • Day 7 – A significant reduction in pain during erection.

  • Day 12 – Patient reported he completely pain free, very pleased as he was able to have pain-free sexual intercourse.

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Peyronies 1 pre tx .jpg

Pre treatment

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Peyronie's 2 post tx.jpg

Post treatment

Why MSTR® Is Well-Placed to Address PD

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Here’s why MSTR® makes sense for PD:

✔ Scar & Fibrosis Expertise

PD plaques are scar tissue, not vascular plaque. Our method is designed specifically to address fascial and connective-tissue scarring which is specific to this problem.

✔ Whole-Body Mechanical Perspective

Scar tissue in one region often reflects broader fascial and mechanical patterns. We assess and treat global tension patterns, not just the local site, because:

  • Fascia is continuous

  • Mechanical load distribution affects tissue repair

  • Compensatory patterns influence symptom persistence
     

This whole-system approach is often missing from conventional PD treatment.

✔ Improving Mobility and Tissue Adaptation

By addressing restrictions in fascial glide, adhesions, and associated soft tissue dysfunction, MSTR® can help:

  • Reduce abnormal stress on the tunica albuginea

  • Improve tissue adaptability

  • Support healthier collagen integration

Although more research is needed (as with all therapies in this field) our clinical experience has shown positive outcomes in men with PD, including reductions in pain, improved comfort during erections, and enhanced functional mobility. Results vary and evidence is continuing to emerge. Statutory notice: MSTR® is not diagnostic and is not a substitute for medical care

What men often experience after MSTR® for PD

7

Some of our MSTR® practitioners have reported that men with PD may experience:

  • Reduced plaque stiffness or discomfort

  • Improved penile flexibility

  • Reduction in or elimination of painful erections

  • Enhanced sexual confidence and comfort

  • Elimination of pain during sexual intercourse

  • Better continuum of fascial movement through pelvic and abdominal regions
     

These outcomes reflect not just localized change, but improvements in overall mechanical environment and scar tissue behavior.

Moving Forward with Confidence

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If you or someone you know is affected by Peyronie’s disease, know that help is available.

 

Whilst PD has historically been under-discussed, emerging insights into fascia, scar tissue biology, and mechanical loading are opening new ways to approach this condition.

MSTR® offers a unique, principled method grounded in connective-tissue science and we’re proud to be among the first manual therapy systems to bring purposeful, whole-body treatment thinking to Peyronie’s disease and help to millions.

What to expect from your MSTR® practitioner

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Direct vs Indirect Treatment

MSTR® practitioners may offer support for Peyronie’s Disease in one of two ways, depending on their professional scope of practice, insurance coverage, and local regulatory requirements.

Some practitioners (typically physical therapists or pelvic health specialists working within appropriate licensure and insurance frameworks) may be qualified to provide direct manual treatment where permitted. This is always conducted within strict professional guidelines, with clear consent procedures and clinical standards in place.

However, many MSTR® practitioners are not insured or legally permitted to provide direct treatment of the male genital structures.

In these cases, your practitioner will instead offer structured self-application guidance. This approach empowers you to perform the technique yourself in a safe and private setting, while receiving professional education and oversight. For many men, this education-led model is both appropriate and effective.

Your practitioner will clearly explain which option is available within their professional framework and ensure that all care remains ethical, respectful, and within scope.

 

Note: Please be aware some practitioners do not offer either direct or indirect self-treatment guidance.

AND: you should have been medically diagnosed with PD before contacting any of our practitioners. You will be required to produce a written medical report of PD at your first consultation with an MSTR® practitioner.​

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